ResourceLife Sciences
Discover the Selvita cell painting service
10 Oct 2023Cell Painting is a highly multiplexed image-based assay used for cytological profiling. The captured information can be translated via automated image analysis into thousands of numerical features that are used to generate morphological profiles reflecting the biological state of the cells. In this application note from Selvita, explore how the comparison of morphological profiles serves multiple purposes. It can identify the phenotypic impact of chemical or genetic perturbations, elucidate the mode of action, and reveal off-target effects of potential drugs. Therefore, the cell painting methodology can be employed in both preclinical and early discovery programs, providing novel mechanistic insights.