Discriminating Mycobacterial Strains by LC and Multivariate Analysis

This application note demonstrates the use of liquid chromatography of bacterial extracts in the separation of species specific molecular weight mycolic acids. Multivariate analysis of the LC profiles can help the analyst distinguish among the different bacterial species. Tuberculosis is caused by one species of Mycobacteria—there are other species in this genus which are also human pathogens—thus reliable identification of species is critical.