Droplet Digital™ PCR: Detection of DNA Methylation

Bio-Rad’s QX100™ and QX200™ Droplet Digital PCR (ddPCR™) Systems aim to make digital PCR widely accessible, facile, and affordable. This application note demonstrates the unprecedented sensitivity, linearity, and robustness of DNA methylation detection by ddPCR in the SNRPN promoter, a model system for an imprinted gene involved in neurological disorders.