ResourceGeneral Lab

Effect of Diluent on Analyte Adsorption to Glass Vials

21 Nov 2014

Silanol groups present on the surface of Type I autosampler glass vials contribute to quantitative loss in the case of basic analytes. This is believed to occur primarily by electrostatic interaction and possibly by hydrogen bonding to some degree. In this white paper, the nature of this interaction was investigated in a series of experiments using different sample diluents.

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