Enhanced plasmid production – Achieving a 21-fold increase in plasmids

The demand for plasmid DNA (pDNA) has increased over the last few years as a result of the high demand for gene therapies and DNA vaccinations. Therefore, an increased production of pDNA with a cost-effective, reproducible, and reliable purification and quality control system is required. Explore how the combination of the Ultra Yield^® flasks with the enriched Plasmid+^® medium and the AirOtop^® enhanced seal led to higher cell densities and a 21-fold higher amount of plasmid than in Erlenmeyer shake flasks with LB medium.