Establishment of clonal organoid cultures after CRISPR-Cas9 genome editing

In this whitepaper, Yamaha Motor Co. and HUB demonstrate the ability of the Yamaha CELL HANDLER™ to select CRISPR/Cas9-modified organoids. Download the full note below to explore how this technology can greatly improve the throughput of clonal organoid selection and expansion, and enable the generation of CRISPR clones without any requirement of growth selection — even for experiments with low transfection and or Cas9 modification rates.