Evaluation of hMATE₁ and hMATE₂-K Activity using Primary Human Kidney Cells

This poster demonstrates the use of cultured human kidney cells as a suitable tool to assess potential hMATE₁ and hMATE₂-K mediated drug-drug interactions involving cationic/zwitterionic drugs that are subject to renal secretion. Analysis is carried out using a multi-mode microplate reader to measure intracellular fluorescence.