Examination of Proposed Manufacturing Standards Using Low Template DNA

Forensic DNA laboratories rely on reagent and plastics manufacturers to supply high-quality products with minimal interference from contaminating DNA but with the increasing sensitivity of short tandem repeat (STR) amplification systems, levels of DNA that were previously undetected may now generate partial profiles. This poster explores the limit of detection for the analysis methods currently being used and what level of contaminating DNA would interfere with analysis in customer labs thorough determination of the sensitivity of STR analysis and comparison to qPCR analysis and.