Extraction and Isolation of a Natural Product from Schisandra Berry Extract using SFE and SFC

Berries of schisandra (Shisandra chinensis) have been widely used for medicinal purposes in traditional Chinese medicines for centuries. The berries contain a wide variety of organic compounds with dibenzo[a,c]cyclooctadiene lignans being of particular interest. This application note demonstrates the feasibility of using the Prep100q SFC System as a tool for isolating schisandrin A from dry schisandra berries extract using supercritical fluid extraction (SFE).