Fast and Reliable Identification of Drugs and their Metabolites Using LC-MS/MS Ion Trap Analysis and a Comprehensive Spectral Library of Almost 4500 Compounds

Comprehensive screening of urine samples in forensic toxicology and clinical research is focused on the unambiguous identification of parent drugs and their corresponding metabolites. This study presents the evaluation of a comprehensive and robust forensic toxicology LC-MSn ion trap spectral library based forensic screening solution to detect and confirm both parent drugs and metabolites in urine as alternative or complementary technology to GC-MS.