Fast and Reproducible Method for Cell Disruption

A very efficient method of cell disruption is bead beating, where cells in suspension are mechanically disrupted by glass beads in single use reaction vials. In this application note, the RETSCH Mixer Mill MM 400 in combination with the Falcon tube adapter is used to make the cell disruption process reproducible, fast and efficient. The effectiveness of the method is demonstrated using examples of cell disruption of yeast cells (Saccharomyces cerevisiae) and microalgae cells (Thalassiosira pseudonana and Phaeodactylum tricornutum).