Flow Synthesis: Reaction Optimisation and Scale-up in Meso-reactors

Continuous flow-through chemistry is an emerging technology for reaction optimisation and scale-up that has broad applicability in early stage drug discovery. In this application poster the FlowSyn™, an integrated bench-top continuous flow reactor, is used for an SN_Ar synthesis of a zyvox® intermediate, and a Knorr pyrazole synthesis reaction.