Fully automated simultaneous analysis of cephem antibiotics in serum by LC-MS/MS

Cephem antibiotics like penicillin and carbapenems are a type of β-lactam antibiotic used in oral medicines and injectable solutions. Cephem antibiotics are said to be effective for various illnesses because they have a high safety profile with a low frequency and degree of side effects.

In this application note, Shimadzu introduce a simultaneous analysis method for cephem antibiotics in blood plasma by LC-MS/MS using the CLAM-2030, which enables fully-automated pretreatment of biological samples.