Generation of Automated Label-Free Cell Migration Assays through the Incorporation of Magnetic 3D Bioprinting

Three-dimensional (3D) cell culture platforms are potential solutions as they can reconstruct tissue structure and environments in vitro. This application note presents two bioprinting procedures that were created to allow 3D wound healing and metastatic cell movement to take place in vitro. Final combined processes were tested using multiple skin and cancer cell models in 384-well format to demonstrate that the incorporation of 3D magnetic bioprinting can lead to the generation of in vivo-like cell migration data.