Global Gene Expression Changes Induced in Primary Human Hepatocytes by Thiazolidinediones upon Repeat Dosing of HepatoPac Cultures

This poster demonstrates an attempt to discern the effects of acute (24 hours) and chronic (7 to 14 days) drug exposure on the transcriptome of primary human hepatocytes using the hepatotoxic and non-toxic drug pair, Troglitazone and Rosiglitazone, respectively.