High Mass Resolution is Essential for Confident Compound Detection

Analytical laboratories are under ever-increasing pressure to deliver fast results, while maintaining the highest levels of accuracy and confidence. The majority of these laboratories rely on targeted analytical approaches, using both gas chromatography and liquid chromatography coupled to triple quadrupole mass spectrometry (MS) instrumentation. These techniques cover the wide range of chemical classes to be monitored at the required levels of sensitivity and selectivity. However, they are limited to those compounds in the target list and they require careful optimization of acquisition parameters for each compound. This application note explains how high resolution, full scan mass spectrometry provides a solution to the demand for detection and quantification of a growing number of compounds and the retrospective analysis of samples long after data acquisition.