High Sensitivity SISCAPA-Based Peptide Quantitation Using UHPLC and the 6490 QQQ with iFunnel Technology

Assays that are both specific and quantitative for target proteins and peptides are critical for preclinical validation of putative biomarkers, particularly those at low concentrations in plasma, where absolute instrument sensitivity has been a key limitation. This application note demonstrates the use of an integrated, automated, high-throughput MS-based protein assay platform.