High-throughput analysis of 1,4-dioxane in drinking water using SPME Arrow–trap with multi-step enrichment (MSE)

In this application note, Markes International presents a study in which solid-phase microextraction (SPME) Arrow–trap with multi-step enrichment (MSE^®) on the Centri^® extraction and enrichment platform was combined with gas chromatography–mass spectrometry (GC–MS) to analyze levels of the contaminant 1,4-dioxane in water samples. The system detected 1,4-dioxane at the lowest calibration point of 0.01 µg/L (10 ppt), which is beyond the detection limits required in German REACH and US EPA regulations.