High-throughput Screening Method for Multiple Classes of Antibiotics in Milk Using Automated Sample Preparation and LC-MS/MS

This application note presents a new online LC-MS method for the simultaneous screening of different classes of antibiotics in milk. The automated TurboFlow LC-MS/MS method improves the laboratory throughput by significantly minimizing the necessary sample preparation while still allowing limits of detection of low ppb levels. Representative SRM chromatograms of a neat standard, whole milk, and fat-free milk sample containing 100 ppb of the veterinary drugs are shown.