High Throughput Screening of Compounds Affecting Distinct Phases of the Cell Cycle Using No Wash Assays

This application note demonstrates how the MultiCyt™ Cell Cycle Screening Kit and the iQue™ Screener can be employed for high throughput assays that accurately determine cell cycle perturbations across of wide variety of known cell cycle inhibitors. Compounds were selected for their diverse mechanisms of action, including DNA polymerase inhibitors, topoisomerase inhibitors, and compounds that alter microtubule structure.