High-Throughput Tools for Optimizing Drug Nanosuspensions

This application note describes a method for early process development of a compound in nanoparticle format that is rapid and requires very little material. This method is ideal for the early discovery phase, where limited amount of the compound is available. As part of the method, particle size measurements of the nanosuspensions were obtained using a DynaPro Plate Reader Wyatt Technology Corp., which performs dynamic light scattering (DLS) in situ.