How imaging mass cytometry technology uniquely detects low-abundance biomarkers

This technical note outlines why the high dynamic range of IMC technology is critical for protein quantification and enables the assessment of expression level without saturation of signals. It also outlines the significance of detecting low-level marker expression (highlighting PD-1, PD-L1 and CTLA-4); how IMC technology allows for clear analysis of low-abundance markers, and examples of PD-1, PD-L1 and CTLA-4 marker expression analysis using IMC systems.