Identification and Quantification of Illegal Drugs and Benzodiazepines in Human Plasma by LC/MS/MS Analysis After Solid Phase Extraction

Identification and quantification of drugs of abuse in blood plasma is common place in forensic medicine and toxicology labs. This application note from Gilson describes an automated SPE protocol using a Gilson GX-271 ASPEC™ system for the simultaneous extraction of amphetamines, cocaine and its metabolites in addition to benzodiazepines prior to analysis by GC/MS or LC/MS.