Identify stable biologic candidates during cell line development with Aura PTx

This application note showcases how Aura PTx enables early characterization of antibody stability during CHO cell line development. By utilizing high-throughput, low-volume subvisible particle analysis, Aura PTx assesses the physical stability of secreted antibodies in unfiltered samples. The method supports informed candidate selection and enhances biologic developability from the start, addressing challenges posed by complex biologic modalities and high titer demands.