Immuno-PET: PET Imaging Using Radiolabeled Antibodies

Antibody targets can be identified and generated for a variety of applications including cancer detection and staging, tumor and metastasis phenotyping, stratification of patients into treatment groups and the evaluation of tumor targeting and therapy response. Once the optimal antibody has selected, it can be labelled with a radionuclide, a combination used for Immuno-PET imaging. This application note demonstrates how immuno-PET can be used to detect virtually any cell surface tumor biomarker, and precise target selection can yield valuable information about the tumor e.g. location, phenotype, susceptibility to therapy, and treatment response.