Important aspects to consider about GLP-1 and GIP

Reports showing that glucagon-like peptide (GLP-1) lowers glucose levels, and glucose-dependent insulinotropic polypeptide (GIP) stimulates insulin secretion led to the development of the first GLP-1 receptor agonist exenatide, followed by the dual GIP and GLP-1 receptor agonist tirzepatide. Uncover the importance of accurate quantitative methods for the precise measurements of these molecules, and explore some of the significant analytical factors that should be considered when measuring circulating GLP-1 and GIP.