Improved Clean Up and Recovery of Pharmaceutical Compounds From Plasma

Diclofenac is a post-operative pain reliever that has also been shown to diminish the formation of the pro-inflammatory hormones. This application note describes the use of two popular extraction methods, solid phase extraction (SPE) and liquid-liquid extraction (LLE), for the isolation of diclofenac from plasma using Strata-X SPE. This article demonstrates the capability of Strata-X SPE to retain hydrophobic neutral compounds as well as acidic and basic compounds.