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Increasing Sensitivity and Minimizing Sample Volume for the Quantification of Therapeutic and Endogenous Cyclic Peptides Using an Integrated Microfluidic Device
Increasing Sensitivity and Minimizing Sample Volume for the Quantification of Therapeutic and Endogenous Cyclic Peptides Using an Integrated Microfluidic Device
15 Jul 2015This application note investigates the improved sensitivity and decreased sample volume requirements for the therapeutic and endogenous cyclic peptides. This method uses selective µElution mixed-mode SPE sample preparation and optimized MS precursor and fragment choice to avoid the need for large sample volumes.