Introducing Precellys: A tool for nano-milling poorly water-soluble API

In this application note, Bertin Technologies validates the use of Precellys^® 24 with Cryolys for nano sizing of poorly water-soluble drugs using different milling protocols. The study was performed using different parameters such as bead diameter, bead concentration, and material. The study showed that the Precellys with Cryolys represents a new technology for drug nano-milling that can be utilized in early discovery and preclinical research.