Introduction to Technological and Multimodal Advances in Preclinical PET Imaging

This application note provides an introduction to preclinical PET imaging, and the benefits associated with it. Preclinical PET imaging produces quantitative, spatially and temporally indexed information on normal and diseased tissues. Importantly, because of the non-invasive nature of the technique, imaging allows longitudinal (serial) study of animal models of human disease. Not only does this minimize the number of experimental animals required, it also gives results in real time, reducing the need for expensive and labor intensive histology.