Investigation of Protein:Protein Interactions (PPI) using a Novel Bioluminescence Resonance Energy Transfer (BRET) Proximitybased, High Throughput Screening Assay

This application note describes a study investigating dynamic protein:protein interactions within a biologically relevant environment, using a live-cell Bioluminescence Resonance Energy Transfer (BRET) assay. This assay method used a Synergy™ Neo2 for rapid detection of multiple signals.