Label-Free CAR-T Cell Assays with the Corning® Epic® BT: A High Throughput Kinetic System

Chimeric antigen receptor (CAR)-T cells, which contain a single chain variable fragment to recognize tumor cell surface antigens, have shown promise as a new tool in immunotherapy, with best case clinical results of total cancer remission in patients with B-cell lymphoma. This study demonstrates that the Corning Epic BT system is capable of performing label-free kinetic CAR-T assays at physiologically relevant temperatures.