Label-free Screening of Human Diseases

Autoimmune diseases are derived from autoimmunity and are caused by an immune response of the organism against its own cells and tissues because it does not recognize them as own constituent parts. One example for an autoimmune disease is the Hughes syndrome (antiphospholipid syndrome, APS). Hughes syndrome is derived from antibodies against cell-membrane phospholipid (aPL) resulting in thrombosis and complications during pregnancy like stillbirth, pre-term delivery, miscarriage or preeclampsia. This application note demonstrates how the Berthold Technologies bScreen with Biametrics 1lambda-RIDe technology is able to detect specifically serological autoimmune antibodies and thus can help to diagnose autoimmune diseases more quickly.