Large-Scale Production of Human Mesenchymal Stem Cells in BioBLU® 5c Single-Use Vessels

Stem cell-based regenerative medicine has great potential to revolutionize human disease treatments. Among the various stem cell platforms, mesenchymal stem cells represent one of the highest potentials as evidenced by clinical trial activities. This study demonstrates the success of large clinical-scale culture of human adipose-derived mesenchymal stem cells in an industrial single-use vessel at 3.75 liter (L) scale. The vessel offers a precision controlled environment for the ideal growth of stem cells under simulated physiological conditions.