Latex-Enhanced Immunoturbidimetric Assay for the Determination of 11-Dehydro Thromboxane B2 in Urine as New Analytical Tool for the Study pf Aspirin Effectiveness

The measurement of stable metabolites of thromboxane A2(TxA2), such as urinary 11-dehydro thromboxane B2(11dhTxB2), allows the determination of the production of TxA2 by platelets and the assessment of the effectiveness of aspirin therapy. This study presents the performance evaluation of a latex-enhanced immunoturbidimetric assay to determine levels of 11dhTxB2 in human urine.