LC-MS/MS Analysis of Microcystins in Drinking Water on EVOQ™ Elite

This application note describes an LC-MS/MS method developed for analysis of mirocystins in drinking water by direct injection on EVOQ Elite model triple quadrupole mass spectrometer. The method is sensitive to detect 0.05 ppb microcystins in water with good reproducibility (RSD ≤ 10%, n=7), and with excellent linear calibration range from 0.05 to 50 ppb.