LC/MS/MS Analysis of Oxytocin and ARG-Vasopressin in Human Plasma/Serum Using Strata™-X-CW Solid Phase Extraction and a Luna® PFP(2) HPLC Column

Interest in oxytocin and ARG-vasopressin has recently piqued since studies have linked autism to polymorphisms in genes associated with receptors in the vasopressin-oxytocin pathway. It has also been postulated that OT and AVP be used as targets for novel approaches to clinical intervention. This study provides an accurate and reproducible method to analyze both OT and AVP in one injection.