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LC-MS of intact therapeutic monoclonal antibodies using Agilent AdvanceBio RP-mAb
15 Jul 2021In this application note, Agilent Technologies analyze multiple therapeutic monoclonal antibodies (mAbs), including an antibody drug conjugate (ADC), using AdvanceBio RP-mAb columns in an LC-MS method. This approach delivered fast analysis times and accurate mass determination of intact mAbs.