Lipotype Skin Lipidomics

The lipid composition of human skin is essential for its function. However, the simultaneous quantification of a wide range of stratum corneum and sebaceous lipids is not trivial. Lipotype developed and validated a quantitative high-throughput shotgun mass spectrometry-based platform for lipid analysis of tape-stripped skin samples. Lipotype analyzes also other types of skin samples, from monolayers to 3D models. It is now easy to investigate how the healthy skin lipidome is composed, how it changes in diseases or upon intervention with a drug or a cosmetic product. This lipidomic data can be used for cosmetic claim support, topical drug development and personalized cosmetics.