Low Light Imaging of Reactive Oxidative Species within Wound Sites Using Luminol

The iBox Scientia is a powerful tool for imaging disease processes within an in vivo model. In this application note, luminol was used in vivo to monitor the generation of ROS, specifically due to the inflammatory response mounted by phagocytic cells. Through the use of luminescence, real-time imaging of ROS generation by inflammatory cells can be observed evolving within the wound of a mouse.