Lysate Clearance Using the AcroPrep™ Advance Filter Plate

Molecular biology methods have led to the successful production of a variety of synthesized biomolecules (DNA, RNA, proteins) from prokaryotic and eukaryotic cell lines. The most problematic step in the purification of these biomolecules is the clarification of the sample once the cells are lysed. This application note presents a lysate sample preparation procedure using the AcroPrep™ Advance filter plate for lysate clearance that effectively removes unwanted cellular debris from samples.