Metabolomic differential analysis of gene-mutated Drosophila using LC/MS and GC/MS

In this application note, Shimadzu presents examples of analyses to compare wild and genetically mutated Drosophila and analyze differences in metabolites. Long-lived gene mutations were generated in Drosophila yellow, and metabolites in wild and mutant Drosophila were measured by liquid chromatograph mass spectrometer (LCMS-8060NX) and gas chromatograph mass spectrometer (GCMS-TQ^™ 8040 NX).