Miniaturization of Multiple Displacement Amplification (MDA) of Genomes from a Single Cell

Advances in whole-genome amplification have enabled sequencing of DNA and RNA from a single cell, or what is commonly called Single-cell Genomics (SCG). However in a recent Nature Protocols article, researchers at the Department of Energy Joint Genome Institute describe an approach that can meet the throughput and sample quality required for robust whole genome amplification from a single cell. This application highlight, describes the role of the Echo liquid handler in this new approach.