Miniaturized High Throughput Kinase Screening Using the Echo® Liquid Handler and Access™ Workstation

Small molecule screening against kinases is commonly used to discover drug candidates that target various human diseases. By combining the nanoliter-scale and non-contact Labcyte Echo 525 liquid handler with the robust and ultra-sensitive Promega ADP-Glo assay, high throughput screening can be improved. This poster demonstrates the reproducibility of inhibition and IC50 determinations from a high throughput screen performed with the Echo 525 liquid handler.