Modeling Cardiac Hypertrophy: Endothelin-1 Induction with High Content Analysis

This Application Protocol describes how to utilize iCell Cardiomyocytes in a 5-day post-plating in vitro cellular model of cardiac hypertrophy that is induced by endothelin-1 (ET-1) and quantified via increased BNP expression using a screening-compatible 384-well assay with high content analysis.