Multiplexed High Content Screening Assays for Cell Cycle Analysis and Cytotoxicity Profiling

Cell proliferation and cell cycle analysis play critical roles in drug discovery. Modulation of cell division has implications for a broad variety of target processes e.g. oncogenesis, angiogenesis, apoptosis and inflammation. Cellular proliferation also represents a sensitive marker of cytotoxicity. High Content Screening (HCS) is a powerful tool for detailed investigation of cellular responses to pharmacological compounds. In this poster read how a panel of platform-independent immunofluorescence-based assays are used for HCS cell cycle analysis.