Multiresidue Pesticides in QuEChERS Extracts of Finished Tobacco Using GCxGC-TOFMS

In this application note, the QuEChERS sample preparation approach was used to isolate residues prior to analyzing pesticides in tobacco. The cleanup efficacy and pesticide recoveries were evaluated for different formulations of QuEChERS dispersive solid phase extraction (dSPE) cleanup and the more traditional cartridge solid phase extraction (cSPE) cleanup. Comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry (GCxGC-TOFMS) was used to determine pesticide residues in the resulting extracts.