N-linked Glycan Characterization and Profiling: Combining the Power of Accurate Mass, Reference Glucose Units, and UNIFI Software for Confident Glycan Assignments

This application note details a new workflow for a glycan assay, using FLR with mass confirmation, available in the latest version of the Biopharmaceutical Platform Solution with UNIFI. The practical use of this workflow for fluorescent labeled (2AB) N-linked released glycan characterization is illustrated using a biosimilar/innovator biotherapeutic comparability study.