NanoPro™ Assay: Lactate Dehydrogenase (LDH)

This application note describes the use of an immunoassay platform to investigate protein complexes of lactate dehydrogenase (LDH). Functional lactate dehydrogenase is a homo or hetero tetramer composed of LDHA and/or LDHB. Here, quantitative analysis of LDHA and LDHB in WM35 cells is performed. LDH over expression and differential expression of LDH isoforms have been implicated in the pathogenesis and progression of many cancers.