New Automated Systems for Size-Fractionation of Protein Samples

This application note describes two new systems for automated preparative electrophoresis of protein samples. It is demonstrated that these systems provide increased reproducibility and ease-of-use for procedures that require gel isolation of proteins, such as top-down proteomics studies and other protein mass spectrometry methods. The BluePippin system is useful for applications where a single targeted fraction containing a protein of interest is needed. The ELF system is useful for broader proteomic studies including top-down proteomics and GeLC-MS.